Owen Farrell has been named at fly-half for England’s autumn series opener against South Africa at Twickenham on Saturday.

The Saracens playmaker starts in the position for only the third time in the Eddie Jones era, forcing George Ford to settle for a place among the replacements.

In a gamble by Jones, Ben Te’o has been picked at inside centre despite being limited to only 28 minutes of rugby since May due to thigh and calf injuries.

The inclusion of Te’o means Manu Tuilagi is confined to a bench a role where he will win his first cap since 2016 as an impact substitute.

Chris Ashton has failed to make the matchday 23 altogether with Jonny May and Jack Nowell preferred on the wings.

Completing the backline is Henry Slade’s inclusion at outside centre, the position he filled throughout the 2-1 series defeat by the Springboks in June.

Filling the void left by an injury crisis at number eight is Mark Wilson, who will be winning his fifth cap in the absence of Billy Vunipola and Nathan Hughes.

Brad Shields returns at blindside flanker and Tom Curry continues in the number seven jersey in a back row containing a mere 10 caps.

Alec Hepburn has held off the challenge of Exeter club mate Ben Moon to start at loosehead prop and the uncapped Zach Mercer features on the bench.

Dylan Hartley, co-captain alongside Farrell, has more caps than the rest of the pack put together having made 93 international appearances.

England return from their week-long Portugal training camp on Thursday night to begin final preparations ahead of the first of four Quilter Internationals at Twickenham this month.