The pair will meet at UFC Fight Night 99, which takes place at the SSE Arena in Belfast on Saturday, November 19.
Following a series of injuries, McCall (13-5-1) was forced to sit out on the side-lines and await his return to action.
A string of misfortune then saw two back-to-back bouts cancelled for the California-born fighter at UFC 201 and UFC 203 respectively.
McCall will now step inside the Octagon and face veteran Seery, who the American acknowledges as a challenger who always comes to fight.
Seery (16-12-0), meanwhile, will be looking to rally the support of Irish fans in Belfast on the night, as he prepares to face yet another top five contender in UFC’s 125lbs division.
The event will be headlined by a five round welterweight bout between South Korea’s Dong Hyun Kim (21-3-1) and Gunnar Nelson (15-2-1) who trains out of Dublin’s Straight Blast Gym.
Also set to feature on this exciting fight card is a women’s strawweight bout between Denmark’s Anna Elmose, who moves up to 115lbs, and finalist of The Ultimate Fighter, Amanda Cooper.
Tickets to Kim vs Nelson will be available to the general public on Friday, September 23.
UFC Fight Club members will be able to secure their ticket early on Wednesday, September 21.