Having now fully recovered from injury, Alexis Sanchez has come into the starting XI – at the expense of Marcus Rashford.

Rashford, who turned 21 last week, had been given a start up front in place of the misfiring Romelu Lukaku, but now it is Sanchez’s turn to impress.

Lukaku’s fortune has taken another nosedive as he has not even been named on the bench by Jose Mourinho. Reports suggest that he picked up an injury in training on Friday.

Alongside Alexis in a 4-3-3 are Juan Mata and an in-form Anthony Martial, while Fred continues in midfield after coming back into the starting line-up in the victory over Everton last weekend.