Holders Sevilla will have to win in Russia to keep their defence on track after the Spanish side were drawn to play Zenit St Petersburg in the Europa League quarter-finals.

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In-form Bundesliga side Wolfsburg host Napoli in the first leg of their last-eight matchup while Dynamo Kiev await the second Italian side Fiorentina.

Wolfsburg, who lie second in the German top flight, and fourth-placed Serie A outfit Napoli have never met previously in European competition.

The 2009 German champions enjoyed their best run in the competition in 2010, when they reached the quarter-finals, while Napoli memorably won the former UEFA Cup in 1989 when Diego Maradona inspired them to a 5-4 aggregate victory over Stuttgart.

Finally Club Brugge face a tricky task as they were drawn to take on Ukraine’s Dnipro Dnipropetrovsk. Sevilla, who crushed domestic rivals Villarreal 5-2 on aggregate to reach the last eight, have met the 2008 winners four times including a quarter-final triumph in 2006 when they went on to win the UEFA Cup.

Sevilla have beaten opposition from Ukraine three times in four matches while Zenit have not beaten a Spanish team in their last seven fixtures and have won just twice in 14 matchups against Liga opposition.

Sevilla’s technical secretary Oscar Arias admitted it was a tough draw for the team who also won the tournament in 2007.

“At this stage, the sides in the draw deserve to be there and Zenit are one of the strongest sides in the draw,” he said. “It will be a very open but difficult game and we know we have to travel a long way, and that’s a handicap, but that’s the way the draw has worked out and it cannot be an excuse.”